This case also illustrates that cystic degeneration of a subserosal uterine fibroid is a differential diagnosis of ovarian tumor in pregnancy . Cystic degeneration is an extreme sequel of edema. Differential diagnosis of a malignancy should be considered in women presenting with a uterine mass, particularly if they are postmenopausal.6 One to two in 1000 women with uterine masses are estimated to have a uterine malignancy.7 Suspicion for malignancy is raised for rapidly growing fibroids, particularly in postmenopausal women who are not on hormone replacement therapy, and women responding poorly to gonadotrophin releasing hormone (GnRH) agonists. Frequently, non-fibroid swellings are erroneously diagnosed as adnexal enlargements and their true origin only becomes evident during surgery. Ultrasonography (USG) and CT showed a large mass abutting the uterus extending into the abdomen. Mass was predominantly cystic with septations. Heart, Valve - Degeneration, Myxomatous in a female F344/N rat from a chronic study (higher magnification of Figure 1). hyaline degeneration: [ de-gen″ĕ-ra´shun ] deterioration; change from a higher to a lower form, especially change of tissue to a lower or less functionally active form. CONCLUSION: Uterine cystic tumors are uncommon. Wilde S, Scott-barrett S. Radiological appearances of uterine fibroids. Epidemiology This type of degeneration is thought to represent ~4% of all types of uterine leiomyoma degeneration. Although benign, they can be associated with significant morbidity and are the commonest indication for hysterectomy. Hyaline cystic degenerations of the uterine fibroids may be rare but not uncommon. Fibroids are uncommon before the onset of puberty and regress after menopause. A surgical approach is safe even though not well documented on acute presentations. Being rare in prepubertal females, they commonly accelerate in growth during pregnancy and involute with menopause 1. Fibroadenomas that consist of cysts greater than 3 mm, sclerosing adenosis, epithelial calcifications, and/or papillary apocrine metaplasia are considered as complex fibroadenoma. In this group, histology of the tumor showed a cystic adenomyoma in 3, a congenital cyst in 3, and a blind rudimentary uterine horn in 2 cases, respectively. changes induced by UPA on uterine fibroid architecture or histology [6]. 3 In general, these areas of cystic degeneration are irregular and can appear as a combination of cystic and solid components of variable echogenicity. cAsE rEPOrt A 44-year-old woman was referred to our hospital’s gynecological outpatient clinic due to menorrhagia and The extensive uterine fibroid growth results in a degenerative process, which is usually due to inadequate blood supply . We report a case of sizeable multilocular cystic hydropic degeneration in a uterine fibroid, which evolved during a repeated course of UPA. May show a hypoechoic or heterogeneous uterine mass with cystic areas. Mutations associated with cystic fibrosis can be detected in screening tests. Check for errors and try again. Hyalinization is the commonest type of degeneration. When a fibroid degenerates, it shrinks back to a smaller size that its blood supply can support. Department of Pathology, G.S.V.M. Uterine fibroids, also known as leiomyomas, are the commonest uterine neoplasms. They may also cause pain during sex or lower back pain. When the leiomyoma increases in size, the vascular supply to it becomes inadequate and leads to different types of degeneration: hyaline, cystic, myxoid, or red degeneration. The high salt content in perspiration is the basis for the “sweat test,” which is the definitive diagnostic test for the presence of cystic fibrosis. Background: Fibroadenoma is the most common breast tumor in adolescent and young women.Extensive cystic degeneration in fibroadenoma, so called “cystic fibroadenoma” is rare. Histopathology of the specimen confirmed the diagnosis of cystic degeneration of fibroid uterus in all three cases. Most leiomyomas are intramural, occupying the middle portion of the myometrium. Less frequently it may occur as multiple nodules arising synchronously or asynchronously in the same or in both breasts and may grow very large (upto 20 cm) mainly when it occurs in adolescents. Unable to process the form. Endometrial hyperplasia refers to the thickening of the endometrium. Cystic changes, usually measuring between 1-10 mm, may occur within these benign fibroepithelial tumors. Risk of breast cancer in women with benign breast disease. These findings were interpreted as a rupture of uterine fibroid after cystic degeneration. 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